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Washington Redskins (-2.5) at Minnesota Vikings
The Redskins' running game looked pretty good against the Chargers last week. The Vikings are horrible stopping the run. The Vikings have Adrian Peterson on offense but that's it. Advantage, Redskins. Prediction: Redskins 27, Vikings 17
Jacksonville Jaguars at Tennessee Titans (-12)
It's the Jaguars. Even off a bye it's impossible to think a team this bad can keep a team from covering, let alone win. Prediction: Titans 28, Jaguars 10
Philadelphia Eagles at Green Bay Packers (-1)
No Aaron Rodgers could mean problems for the Packers. The Eagles' defense has looked better of late and Nick Foles has performed well in three of his four outings. The essential pick 'em line makes sense here. This is a tough one to call. Prediction: Packers 30, Eagles 28
Buffalo Bills at Pittsburgh Steelers (-3)
E.J. Manuel should be able to return which could mean bad things for the Steelers. Terrelle Pryor was able to run for a 93-yard read-option touchdown two weeks ago. Manuel has similar capabilities. Prediction: Bills 23, Steelers 20
Oakland Raiders at New York Giants (-7)
The Raiders were exposed by Foles and the Eagles' offense a week ago and will have to defend a similar group of receivers that can make plays downfield. Look for the East Coast trip to not go as planned. Prediction: Giants 31, Raiders 17
St. Louis Rams at Indianapolis Colts (-9)
The Rams are a little late with figuring out their offensive identity but that appears to lie on the shoulders of Zac Stacy for the foreseeable future. Stacy and the running game will do enough to keep the game closer than expected, though the Colts get the win. Prediction: Colts 30, Rams 24
Seattle Seahawks (-6.5) at Atlanta Falcons
The Falcons are a below-average team that's been unable to sustain any momentum. The Seahawks should be able to lock up the suddenly offensively inept team. Prediction: Seahawks 24, Falcons 10
Detroit Lions (-1.5) at Chicago Bears
The Lions are off a bye and the Bears get Jay Cutler back. The Lions, though, may not have Ziggy Ansah in the lineup, which could create more running lanes for Matt Forte. Look for the Bears to get a key divisional win. Prediction: Bears 34, Lions 31
Carolina Panthers at San Francisco 49ers (-6)
Both teams boast some good defenses, with both offenses beginning to peak. However, this could wind up a low-scoring affair. San Francisco gets the edge at home. Prediction: 49ers 17, Panthers 14
Houston Texans at Arizona Cardinals (-3)
The Cardinals defense has been strong of late, with the secondary being a strength. But there aren't many cornerbacks, no matter how talented, that can check Andre Johnson. Houston gets a road win. Prediction: Texans 27, Cardinals 24
Denver Broncos (-7) at San Diego Chargers
Up until last week, Philip Rivers had himself in the MVP conversation. He'll look to get back to that kind of level of play against Denver. The Broncos have susceptible in the passing game at times. But the Chargers will have to keep pace with Peyton Manning and the Broncos. Easier said than done. Prediction: Broncos 41, Chargers 27
Dallas Cowboys at New Orleans Saints (-6.5)
Rob Ryan gets to face his former employer with hopes of sending them back across the Texas/Louisiana border unhappy. Assuming Darren Sproles is cleared through the concussion protocol, the Saints could put up a ton of points in a revenge game. Prediction: Saints 38, Cowboys 27
Miami Dolphins (-2.5) at Tampa Bay Buccaneers
The Monday Night Football folks could have never guessed this game would have so many storylines for all of the wrong reasons. Bullying in Miami. A coaching catastrophe in Tampa. These two combined with Jacksonville have disappointed the state of Florida in 2013. Prediction: Dolphins 24, Buccaneers 20